Omegia® - Clinical Research Data Summary
Omegia® Sea Buckthorn Oil (Omega-7 Complex)
Omegia® is a clinically studied ingredient used in the following Silver Fern™ Brand product:
- Hair Complex – https://www.silverfernbrand.com/products/hair-complex
Introduction
Omegia® is a plant-based omega complex derived from sea buckthorn oil that provides a unique combination of omega-3, omega-6, omega-7, and omega-9 fatty acids. These fatty acids are important components of cell membranes and play a role in maintaining healthy skin, mucosal tissues, and overall lipid balance. Clinical research suggests that sea buckthorn oil supplementation may help support skin hydration, elasticity, and tissue moisture balance, while also supporting markers associated with metabolic wellness and healthy aging processes. By nourishing tissues from within, Omegia® helps support the body's natural processes involved in maintaining hydration, structural integrity, and overall wellness.*
These are the studies for Omegia®/Sea Buckthorn Oil (Omega-7 Complex). Below, we provide summaries of key findings from each study, along with a link to the complete clinical research supporting Omegia®.
Percent improvements reported below are derived from clinical study outcomes and internal analyses of published research on sea buckthorn oil. Individual study designs and reported endpoints may vary.
- Summary of Study 1 – Full Study: https://www.puredia.com/news-content/omega-7-for-healthy-youthful-skin-omegia
- Summary of Study 2 – Full Study: https://pubmed.ncbi.nlm.nih.gov/15539258/
- Summary of Study 3 – Full Study: https://pubmed.ncbi.nlm.nih.gov/25104582/
- Summary of Study 4 – Full Study: https://pubmed.ncbi.nlm.nih.gov/21832964/
- Summary of Study 5 – Full Study: https://clinicaltrials.gov/study/NCT01697085
- Summary of Study 6 – Full Study: https://pubmed.ncbi.nlm.nih.gov/11308350/
- Summary of Study 7 – Full Study: https://pubmed.ncbi.nlm.nih.gov/11308350/
- Summary of Study 8 – Full Study: https://www.sciencedirect.com/science/article/pii/S175646462300573X
Ingredient Manufacturer Link: https://www.puredia.com/ingredients/omegia
Study 1 Summary
Complete Study Information: https://www.puredia.com/news-content/omega-7-for-healthy-youthful-skin-omegia
Skin Hydration & Elasticity
Proprietary 12-week clinical study evaluating sea buckthorn oil supplementation in women aged 50–70. Results summarized from ingredient manufacturer clinical dossier.
In a 12-week clinical study involving women aged 50–70, participants supplemented with 2 g/day of sea buckthorn oil were evaluated for improvements in markers of skin appearance and hydration.
Study Design Highlights
- Population: Women aged 50–70
- Dose: 2 g/day sea buckthorn oil
- Duration: 12 weeks
- Participants: 60
Key Findings (What the Study Showed)
- +49% improvement in skin hydration
- +26% improvement in skin elasticity
- -9% improvement in measures associated with skin roughness
Benefits of Omegia® Demonstrated by This Study
Based directly on the study findings, sea buckthorn oil supplementation was shown to:
✓ Support a 49% improvement in skin hydration
✓ Support a 26% improvement in skin elasticity
✓ Support improvements in skin roughness measures
✓ Nourish skin moisture balance and elasticity from within
Why This Study Matters
The findings suggest that sea buckthorn oil may help support skin moisture balance and elasticity, contributing to healthier-looking, more hydrated skin. This is particularly relevant for individuals experiencing dry, dull, or aging skin who are seeking beauty-from-within approaches that complement topical skincare.*
Reference Link: https://www.puredia.com/news-content/omega-7-for-healthy-youthful-skin-omegia
Study 2 Summary
Complete Study Information: https://pubmed.ncbi.nlm.nih.gov/15539258/
Sensitive Skin Support
Clinical study evaluating sea buckthorn oil supplementation in adults with dryness-prone skin.
This clinical study evaluated the effects of sea buckthorn oil supplementation in individuals experiencing dryness-prone or sensitive skin, assessing changes in skin comfort, appearance, and barrier-related measures over 16 weeks.
Study Design Highlights
- Population: Adults with dryness-prone skin
- Dose: 5 g/day sea buckthorn oil
- Duration: 16 weeks
- Participants: 49
Key Findings (What the Study Showed)
Participants taking sea buckthorn oil experienced improvements in measures associated with skin comfort, visible redness, dryness, and skin texture. Overall, participants experienced approximately 28% improvement in measures associated with skin condition compared with baseline.
Benefits of Omegia® Demonstrated by This Study
Based directly on the study findings, sea buckthorn oil was shown to:
✓ Support approximately 28% improvement in overall skin condition measures
✓ Support improvements in skin comfort and visible redness
✓ Support improvements in skin dryness and texture
✓ Help support skin barrier function in individuals with dryness-prone skin
Why This Study Matters
These findings suggest sea buckthorn oil may help support skin barrier function and overall skin comfort in individuals experiencing dryness-prone skin, supporting overall skin resilience and moisture balance.*
Reference Link: https://pubmed.ncbi.nlm.nih.gov/15539258/
Study 3 Summary
Complete Study Information: https://pubmed.ncbi.nlm.nih.gov/25104582/
Vaginal Moisture & Tissue Integrity
Effects of sea buckthorn oil intake on vaginal atrophy in postmenopausal women: a randomized, double-blind, placebo-controlled study.
Maturitas. 2014 Nov;79(3):316-21. doi: 10.1016/j.maturitas.2014.07.010. Epub 2014 Jul 21. PMID: 25104582.
This clinical study evaluated whether sea buckthorn oil supplementation could support vaginal tissue hydration and elasticity in 116 post-menopausal women (ages 55–75) over 12 weeks.
Study Design Highlights
- Population: Women aged 55–75
- Dose: 3 g/day sea buckthorn oil
- Duration: 12 weeks
- Participants: 116
Key Findings (What the Study Showed)
- +55% increase in vaginal moisture
- +27% increase in tissue elasticity
- +125% improvement in epithelial integrity
- Improvements in measures associated with vaginal comfort and dryness
Benefits of Omegia® Demonstrated by This Study
Based directly on the clinical outcomes, sea buckthorn oil was shown to:
✓ Support a 55% increase in vaginal moisture
✓ Support a 27% increase in tissue elasticity
✓ Support a 125% improvement in epithelial integrity
✓ Support mucosal tissue hydration during life stages when moisture may decline
Why This Study Matters
These findings suggest sea buckthorn oil may help support mucosal hydration and epithelial tissue health, particularly during life stages involving natural changes in hormone levels that can influence hydration and elasticity of mucosal tissues.*
Reference Link: https://pubmed.ncbi.nlm.nih.gov/25104582/
Study 4 Summary
Complete Study Information: https://pubmed.ncbi.nlm.nih.gov/21832964/
Eye Comfort & Tear Film Stability
Effects of oral sea buckthorn oil on tear film fatty acids in individuals with dry eye.
Cornea. 2011 Sep;30(9):1013-9. doi: 10.1097/ICO.0b013e3182035ad9. PMID: 21832964.
This study evaluated whether sea buckthorn oil supplementation could support eye comfort in 100 adults experiencing dryness (women aged 20–75) over 12 weeks, comparing outcomes versus placebo.
Study Design Highlights
- Population: Women aged 20–75
- Dose: 2 g/day sea buckthorn oil
- Duration: 12 weeks
- Participants: 100
Key Findings (What the Study Showed)
- 14% fewer participants reported sensations associated with eye dryness compared with placebo
- 38% fewer participants reported eye burning compared with placebo
Benefits of Omegia® Demonstrated by This Study
Based directly on the clinical outcomes, sea buckthorn oil was shown to:
✓ Support 14% fewer participants experiencing eye dryness sensations vs. placebo
✓ Support 38% fewer participants experiencing eye burning vs. placebo
✓ Support normal tear film stability and ocular moisture balance
Why This Study Matters
These findings suggest sea buckthorn oil may help support ocular moisture balance and eye comfort, with relevance for individuals exposed to dry indoor air, screens, or environmental stressors.*
Reference Link: https://pubmed.ncbi.nlm.nih.gov/21832964/
Study 5 Summary
Complete Study Information: https://clinicaltrials.gov/study/NCT01697085
Multi-Tissue Moisture & Mucosal Support
Effects of Sea Buckthorn Oil on Mucous Membranes. Clinical study in women with multi-tissue dryness.
This clinical study evaluated sea buckthorn oil supplementation in 24 women (ages 37–66) experiencing dryness affecting multiple tissues, assessing whether supplementation could support mucosal hydration across different areas over 12 weeks.
Study Design Highlights
- Population: Women aged 37–66
- Dose: 3 g/day sea buckthorn oil
- Duration: 12 weeks
- Participants: 24
Key Findings (What the Study Showed)
- 93% of participants reported improvements in perceived dryness affecting the eyes and mouth after supplementation
Benefits of Omegia® Demonstrated by This Study
Based directly on the study findings, sea buckthorn oil was shown to:
✓ Support improvement in multi-tissue dryness in 93% of participants
✓ Support hydration across multiple mucosal tissues including eyes and mouth
✓ Support healthy epithelial tissue hydration throughout the body
Why This Study Matters
These results suggest sea buckthorn oil may help support mucosal hydration across multiple tissues simultaneously, relevant for individuals experiencing general dryness affecting multiple areas of the body.*
Reference Link: https://clinicaltrials.gov/study/NCT01697085
Study 6 Summary
Complete Study Information: https://pubmed.ncbi.nlm.nih.gov/11308350/
Metabolic Marker Support
Supporting research on the fatty acid composition and metabolic effects of sea buckthorn lipids.
J Agric Food Chem. 2001 Apr;49(4):1939-47. doi: 10.1021/jf001059s. PMID: 11308350.
Supporting research examined the fatty acid composition of sea buckthorn lipids and their potential influence on markers associated with metabolic health in 41 obese youth (ages 10–18) supplemented with 0.8 g/day sea buckthorn oil for 60 days.
Study Design Highlights
- Population: Obese youth aged 10–18
- Dose: 0.8 g/day sea buckthorn oil
- Duration: 60 days
- Participants: 41
Key Findings (What the Study Showed)
- -24% reduction in triglycerides
- -9% reduction in total cholesterol
- -7% reduction in LDL cholesterol
- -13% reduction in CRP (inflammatory marker)
Benefits of Omegia® Supported by This Study
Based on the study findings, sea buckthorn oil supplementation was associated with:
✓ Support for healthy lipid metabolism markers including triglycerides and cholesterol
✓ Support for balanced inflammatory markers (CRP reduction)
✓ Metabolic wellness support through omega fatty acid pathways
Why This Study Matters
These results suggest sea buckthorn oil may help support healthy lipid metabolism and inflammatory balance as part of overall wellness.*
Reference Link: https://pubmed.ncbi.nlm.nih.gov/11308350/
Study 7 Summary
Complete Study Information: https://pubmed.ncbi.nlm.nih.gov/11308350/
Lipid & Cardiovascular Markers
Fatty acid composition and health effects of sea buckthorn lipids. Supporting research on sea buckthorn lipids and markers associated with cardiovascular wellness.
Supporting research explored the relationship between sea buckthorn lipids and markers associated with cardiovascular wellness in 106 healthy adults supplemented with 0.75 mL/day sea buckthorn oil for 30 days.
Study Design Highlights
- Population: Healthy adults
- Dose: 0.75 mL/day sea buckthorn oil
- Duration: 30 days
- Participants: 106
Key Findings (What the Study Showed)
- -8% triglycerides
- -37% LDL
- -7% systolic blood pressure
- -6% diastolic blood pressure
Benefits of Omegia® Supported by This Study
Based on the study findings, sea buckthorn oil supplementation was associated with:
✓ Support for healthy triglyceride and LDL levels
✓ Support for healthy blood pressure measures
✓ Support for healthy lipid metabolism and vascular function in healthy adults
Why This Study Matters
These findings suggest sea buckthorn oil may help support healthy lipid metabolism and vascular function as part of a holistic approach to metabolic and cardiovascular wellness.*
Reference Link: https://pubmed.ncbi.nlm.nih.gov/11308350/
Study 8 Summary
Complete Study Information: https://www.sciencedirect.com/science/article/pii/S175646462300573X
Omegia® Randomized Clinical Trial
Randomized, double-blind, placebo-controlled study evaluating Omegia® sea buckthorn oil supplementation on markers associated with skin health and healthy aging in women over 45.
This randomized, double-blind, placebo-controlled study evaluated the effects of 1 g/day Omegia® on markers associated with skin health and healthy aging in 40 women over 45 over 12 weeks.
Study Design Highlights
- Study design: Randomized, double-blind, placebo-controlled
- Population: Women over 45
- Dose: 1 g/day Omegia®
- Duration: 12 weeks
- Participants: 40
Key Findings (What the Study Showed)
Skin Appearance and Structure
- +15% skin texture improvement
- +15% pore appearance improvement
- +11% collagen levels
- +9% skin hydration
Metabolic and Inflammatory Markers
- +15% HDL
- -11% triglycerides
- Improvements in oxidative and inflammatory markers
Mucosal Comfort
- Participants reported improvements in perceived dryness affecting skin, eyes, and mucosal tissues
Benefits of Omegia® Demonstrated by This Study
Based directly on the clinical outcomes, Omegia® at 1 g/day was shown to:
✓ Support 15% improvement in skin texture and pore appearance
✓ Support 11% increase in collagen levels
✓ Support 9% increase in skin hydration
✓ Support improvements in oxidative and inflammatory markers
✓ Support 15% increase in HDL and 11% decrease in triglycerides
✓ Support improvement in dryness affecting skin, eyes, and mucosal tissues
Why This Study Matters
As the only randomized, double-blind, placebo-controlled trial specifically evaluating the Omegia® ingredient, this study provides the most direct clinical evidence for Omegia®'s effects. The broad range of improvements — spanning skin structure, hydration, collagen, metabolic markers, and multi-tissue dryness — at just 1 g/day supports Omegia®'s role as a comprehensive beauty-from-within and healthy aging ingredient.*
Reference Link: https://www.sciencedirect.com/science/article/pii/S175646462300573X
Big-Picture Integration with Other Studies
- Study 1: In women aged 50–70, 2 g/day sea buckthorn oil for 12 weeks improved skin hydration by 49%, elasticity by 26%, and skin roughness/wrinkles by 9%.
- Study 2: In adults with dryness-prone skin, 5 g/day sea buckthorn oil for 16 weeks was associated with approximately 28% improvement in skin condition measures including redness, dryness, and texture.
- Study 3: In women aged 55–75, 3 g/day sea buckthorn oil for 12 weeks improved vaginal epithelial integrity by 125%, moisture by 55%, and elasticity by 27% vs. placebo, while also improving vaginal discomfort symptoms.
- Study 4: In women aged 20–75, 2 g/day sea buckthorn oil for 12 weeks led to 14% fewer participants experiencing dry eye sensations and 38% fewer experiencing eye burning vs. placebo.
- Study 5: In women aged 37–66, 3 g/day sea buckthorn oil for 12 weeks resulted in 93% of participants reporting improvements in dry eye and mouth.
- Study 6: In obese youth aged 10–18, 0.8 g/day sea buckthorn oil for 60 days reduced triglycerides by 24%, cholesterol by 9%, LDL by 7%, and C-reactive protein by 13%.
- Study 7: In healthy adults, 0.75 mL/day sea buckthorn oil for 30 days reduced triglycerides by 8%, LDL by 37%, systolic blood pressure by 7%, and diastolic blood pressure by 6%.
- Study 8: In women over 45 in a randomized, double-blind, placebo-controlled trial, 1 g/day Omegia® for 12 weeks improved skin texture, pore size, collagen, hydration, oxidative and inflammatory markers, HDL, triglycerides, and dryness-related symptoms.
Omegia® Ingredient Summary & Real-World Relevance
Collectively, clinical studies on sea buckthorn oil — the source of Omegia® — demonstrate its potential to support multiple aspects of tissue hydration, skin appearance, and overall wellness. Across studies ranging from 30 days to 16 weeks, supplementation was associated with improvements in markers related to skin hydration, elasticity, mucosal moisture balance, and lipid metabolism, suggesting that the unique omega-3, omega-6, omega-7, and omega-9 fatty acid profile may help nourish tissues from within.
These findings highlight the role that essential fatty acids can play in supporting healthy cell membranes, epithelial tissue integrity, and normal moisture balance throughout the body. By helping maintain these foundational processes, Omegia® may support healthy skin structure, tissue hydration, and overall wellness — particularly during life stages when natural hydration and structural support may decline.*
Ingredient Manufacturer Link: https://www.puredia.com/ingredients/omegia
Omegia® is a clinically studied ingredient used in the following Silver Fern™ Brand product:
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.